Article

Surplus sterols suppress Salmonella-specific IgA

Science Immunology
DOI: 10.1126/SCIIMMUNOL.ABN3793
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Abstract

Dietary cholesterol is metabolized into 25-hydroxycholesterol, which decreases intestinal IgA responses by reducing the expression of sterol-sensing transcription factor SREBP2, thereby preventing IgA plasma cell differentiation.

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APA

Liu, E. G., & Eisenbarth, S. C. (2021, December 1). Surplus sterols suppress Salmonella-specific IgA. Science Immunology. American Association for the Advancement of Science. https://doi.org/10.1126/SCIIMMUNOL.ABN3793

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