Síndrome dos cabelos impenteáveis (pili canaliculi): Variabilidade clínica em 12 membros de uma família

Abstract

Pili canaliculi is rare hair disorder, usually inherited as an autosomal dominant trait, clinically characterized by uncombable hair. Few studies report its clinical variability. A family with 12 affected individuals was examined and involvement of hairs ranged from uncombable hairs, mild or intense hypotrichosis to acquired atrichia. Optical microscopy of hair cross sections, stereomicroscopy and scanning electron microscopy confirmed the diagnosis and showed hair shafts with characteristic longitudinal grooves. ©2008 by Anais Brasileiros de Dermatologia.