Recurrent, multifocal mycobacterium avium-intercellulare infection in a patient with interferon-γ autoantibody

Abstract

We describe a patient who experienced severe osteomyelitis because of Mycobacterium avium-intercellulare infection and high-titered autoantibodies against interferon-γ. In addition to antimycobacterial chemotherapy, we treated our patient with plasmapheresis and cyclophosphamide. The treatment induced a remission after 3 years of follow-up. © 2009 by the Infectious Diseases Society of America. All rights reserved.