Synthesis and applications of fluorinated, polyfluoroalkyl- and polyfluoroaryl-substituted 1,2,3-triazoles

Abstract

1,2,3-Triazoles and organofluorine substitutents are both important structural and functional motifs used in a range of applications. This review summarises the confluence of these two important moities and provides a comprehensive account of the methods for synthesising and applying fluorine-, polyfluoroalkyl- and polyfluoroaryl-substituted 1,2,3-triazoles. Focus has been devoted to recent examples and applications where the properties of both the 1,2,3-triazole and organofluorine substituent are proposed to be important in enhancing the compound's functionality.