Abstract
Background Hand hygiene is a fundamental measure for preventing healthcare-associated infections, yet traditional monitoring methods are significantly limited by the Hawthorne effect, high resource demands, and an inability to assess procedural quality. Artificial intelligence (AI) technology has emerged as a transformative, automated, and objective approach to address these long-standing challenges. Objective This scoping review sought to systematically map the existing evidence, technical pathways, performance metrics, and implementation challenges of AI for monitoring hand hygiene compliance in healthcare settings. Methods Following the Joanna Briggs Institute (JBI) methodological framework and PRISMA-ScR guidelines, we searched five major databases (PubMed, Scopus, Embase, Web of Science, and IEEE Xplore) for articles published between January 2000 and September 2025, supplemented by grey literature searching and backward citation tracking. Two reviewers independently screened records, assessed full-text reports for eligibility, and extracted data, which were synthesized using descriptive statistics and thematic analysis. Results Of 800 records identified through database and supplementary searches, 45 studies (2007–2025) were included. The primary technical pathways identified were computer vision (53.3%), wearable sensors (24.4%), Internet of Things-integrated systems (13.3%), and radar/radio frequency-based systems (8.9%). While computer vision achieved high accuracy (95%) in setting-specific ICU models, performance dropped to 56% in generalizable models. Wearable systems demonstrated portability but showed 5%–10% lower specificity than vision-based approaches. Most evidence is derived from small-scale technical validations, with a significant lack of formal fairness analysis and evaluation of clinical workflows or cost-effectiveness. Conclusion AI-based hand hygiene monitoring shows promise for supporting more objective and scalable hand hygiene surveillance in healthcare settings. However, the field remains at a largely pre-translational stage. Future research should shift from technical feasibility toward implementation science, focusing on establishing standardized motion databases, evaluating ethical governance (e.g., privacy and automation bias), and conducting pragmatic trials to demonstrate sustained clinical benefit and organizational sustainability.
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CITATION STYLE
Lin, X., Lv, Y., Xiang, Q., Cai, M., & Wang, P. (2026). Artificial intelligence for monitoring hand hygiene compliance in healthcare settings: A scoping review. PLOS ONE, 21(4 April). https://doi.org/10.1371/journal.pone.0347683
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