Pancreatic cancer foiled by a switch of tumour subtype

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Abstract

Mutations in the gene KDM6A drive an aggressive subtype of pancreatic cancer by causing repositioning of an enzyme complex that modifies histone proteins associated with DNA, leading to altered gene expression.

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Froeling, F., & Tuveson, D. (2018, May 24). Pancreatic cancer foiled by a switch of tumour subtype. Nature. Nature Publishing Group. https://doi.org/10.1038/d41586-018-05129-6

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