Journal Article

An efficient regioselective hydrodifluoromethylation of unactivated alkenes with TMSCF2CO2Et at ambient temperature

Chemical Communications (2014) 50(68) 9749-9752
DOI: 10.1039/c4cc04591b
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Abstract

A mild, versatile and efficient method for the regioselective hydrodifluoromethylation of unactivated alkenes has been developed. This Ag-mediated Csp3–CF2 bond forming reaction provides easy access to a variety of vicinal α-difluoroacetate-containing alkanes. © 2014 The Royal Society of Chemistry.

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Ma, G., Wan, W., Li, J., Hu, Q., Jiang, H., Zhu, S., … Hao, J. (2014). An efficient regioselective hydrodifluoromethylation of unactivated alkenes with TMSCF2CO2Et at ambient temperature. Chemical Communications, 50(68), 9749–9752. https://doi.org/10.1039/c4cc04591b

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