Recurrent invasive pneumococcal disease in individuals with human immunodeficiency virus infection

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Abstract

The proportion of relapses and reinfections that are potentially preventable by vaccine in human immunodeficiency virus (HIV)-infected persons with recurrent pneumococcal disease is unknown. Isolates from HIV-infected individuals from Baltimore with recurrent pneumococcal invasive disease were collected from 1 January 1995 through 31 December 2000. Serotyping and pulsed-field gel electrophoresis were performed. From 1 January 1995 through 31 December 1998, 14.9% (404/2717) of those who had a pneumococcal infection were HIV infected. The recurrence rate among HIV-infected individuals was 6.4-fold higher than that among individuals without HIV infection (P

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McEllistrem, M. C., Mendelsohn, A. B., Pass, M. A., Elliott, J. A., Whitney, C. G., Kolano, J. A., & Harrison, L. H. (2002). Recurrent invasive pneumococcal disease in individuals with human immunodeficiency virus infection. Journal of Infectious Diseases, 185(9), 1364–1368. https://doi.org/10.1086/339882

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