Abstract
A cytotoxic alkylresorcinol was isolated from Lysimachia japonica thunb. (Primulaceae) and identified as grevillol (2). It was tested for cytotoxicity against KB, B-16, PC-13, L-5178Y, P-388, and HEp-2 cells in vitro. Synthetic related compounds were also tested for cytotoxicity against the KB cell line, and the structure-activity relationships are discussed. © 1989, The Pharmaceutical Society of Japan. All rights reserved.
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Arisawa, M., Ohmura, K., Morita, N., & Kobayashi, A. (1989). A Cytotoxic Constituent of Lysimachia japonica THUNB. (Primulaceae) and the Structure-Activity Relationships of Related Compounds. Chemical and Pharmaceutical Bulletin, 37(9), 2431–2434. https://doi.org/10.1248/cpb.37.2431
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