Two cases of fatal shock after transfusion of platelets contaminated by Staphylococcus aureus: role of superantigenic toxins.

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Abstract

We detected Staphylococcus aureus superantigenic toxins in the platelet infusion bags that had been used for 2 patients who subsequently developed transfusion-associated Staphylococcus aureus infection. Both patients, who were immunodeficient, developed manifestations of toxic shock syndrome and septic shock, and they died soon after the onset of infection.

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Perpoint, T., Lina, G., Poyart, C., de Barbeyrac, B., Traineau, R., Jeanne, M., … Etienne, J. (2004). Two cases of fatal shock after transfusion of platelets contaminated by Staphylococcus aureus: role of superantigenic toxins. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, 39(10). https://doi.org/10.1086/425499

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