Calidad de vida relacionada con la salud, factores psicológicos y fisiopatológicos en pacientes con diagnóstico de Lupus Eritematoso Sistémico - LES

Abstract

The aim of this research was to evaluate the impact of anxiety, depression, social support, Systemic Lupus Erythematosus (SLE) disease activity index, fibromyalgia, organic and kidney damage, and time of diagnosis of disease on Health-related Quality of Life in 78 patients with SLE diagnosis. Participants completed the Health Survey Questionnaire (SF-36), the Hospital Anxiety and Depression (HAD) scale, the Duke-UNK Functional Social Support questionnaire, the SLEDAI (SLE Disease Activity Index), and the SLICC/ACR damage index for SLE. As a complementary measure, Fibromyalgia and Nephropathy diagnosis was considered. The results shown that in patients with lupus, pathophysiological (SLE disease activity index and organic damage), psychological (anxiety-depression) and sociodemographic factors (occupation and civil status) affect the quality of life in the mental domain rather than in the physical level. Copyright 2010 by Sociedad Chilena de Psicología Clínica.