Gene conversion: a hitherto overlooked parameter in population genetics

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Abstract

Gene conversion causes deviations from the 2:2 segregation of allele pairs in meiosis. Thus, gene conversion is a potential cause for changes of allele frequencies in populations. Equations are derived for the effects of conversion in a large random mating population. The influence of gene conversion on allele frequencies is compared with that of spontaneous mutation and meiotic drive.

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Gutz, H., & Leslie, J. F. (1976). Gene conversion: a hitherto overlooked parameter in population genetics. Genetics, 83(4), 861–866. https://doi.org/10.1093/genetics/83.4.861

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