Abstract
Alzheimer's disease, a neurodegenerative illness, has the extremely complex pathogenesis. Accumulating evidence indicates there is a close relationship between several enzymes and Alzheimer's disease. Various substituted 3-arylcoumarin derivatives were synthesised, and their in vitro activity, including cholinesterase inhibitory activity, monoamine oxidase inhibitory activity, and antioxidant activity were investigated. Most of the compounds exhibited high activity; therefore 3-arylcoumarin compounds have the potential as drug candidates for the treatment of Alzheimer's disease.
Author supplied keywords
Cite
CITATION STYLE
Yang, J., Zhang, P., Hu, Y., Liu, T., Sun, J., & Wang, X. (2019). Synthesis and biological evaluation of 3-arylcoumarins as potential anti-Alzheimer’s disease agents. Journal of Enzyme Inhibition and Medicinal Chemistry, 34(1), 651–656. https://doi.org/10.1080/14756366.2019.1574297
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
