Curvicollides A-C: New polyketide-derived lactones from a sclerotium-colonizing isolate of Podospora curvicolla (NRRL 25778)

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Abstract

Curvicollides A-C (1-3) have been obtained from cultures of an isolate of Podospora curvicolla (NRRL 25778) that colonized a sclerotium of Aspergillus flavus. The structures of these compounds were elucidated by analysis of one- and two-dimensional NMR data. The lead compound (1) showed antifungal activity against A. flavus and Fusarium verticillioides.

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Che, Y., Gloer, J. B., & Wicklow, D. T. (2004). Curvicollides A-C: New polyketide-derived lactones from a sclerotium-colonizing isolate of Podospora curvicolla (NRRL 25778). Organic Letters, 6(8), 1249–1252. https://doi.org/10.1021/ol0498186

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