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A metabolic strategy to reverse fibrosis?

Nature Metabolism
DOI: 10.1038/s42255-018-0013-8
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Abstract

Fibrosis is characterized by excessive extracellular matrix (ECM) production relative to catabolism. A new study shows that the fuel choice of fibroblasts impacts this balance, with glycolysis promoting ECM synthesis and fatty acid oxidation stimulating ECM degradation.

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APA

Rabinowitz, J. D., & Mutlu, G. M. (2019, January 1). A metabolic strategy to reverse fibrosis? Nature Metabolism. Nature Research. https://doi.org/10.1038/s42255-018-0013-8

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