Sequential asymptomatic enterovirus infections in a patient with major histocompatibility complex class II primary immunodeficiency

Abstract

Patients with primary immunodeficiencies are usually susceptible to enterovirus infections and have higher risks to develop severe clinical forms. We report a unique description of a boy with major histocompatibility complex class II (MHC-II) deficiency infected by 9 different enterovirus serotypes during a 2-year period, with very mild clinical symptoms, probably due to the immunoglobulin therapy he was receiving. Copyright © 2014, American Society for Microbiology. All Rights Reserved.