Abstract
In this issue of Blood, Peffault de Latour et al describe ex vivo measurements of complement activity in paroxysmal nocturnal hemoglobinuria (PNH) patients on eculizumab treatment. This is the first systematic pharmacodynamic (PD) study of eculizumab in PNH patients which shows that CH50 is a promising biomarker of therapeutic complement blockade.
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CITATION STYLE
APA
Risitano, A. M. (2015, January 29). Dissecting complement blockade for clinic use. Blood. American Society of Hematology. https://doi.org/10.1182/blood-2014-12-616300
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