A structure-based model of RIG-I activation

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Abstract

A series of high-resolution crystal structures of RIG-I and RIG-I:dsRNA cocrystals has recently been reported. Comparison of these structures provides considerable insight into how this innate immune pattern recognition receptor is activated upon detecting and binding a certain class of viral RNAs. Copyright © 2012 RNA Society.

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Kolakofsky, D., Kowalinski, E., & Cusack, S. (2012, December). A structure-based model of RIG-I activation. RNA. https://doi.org/10.1261/rna.035949.112

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