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Response to Brinkmann et al. “Re-assembly of 19th century smallpox vaccine genomes reveals the contemporaneous use of horsepox and horsepox-related viruses in the United States”

Genome Biology
DOI: 10.1186/s13059-020-02203-z
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Abstract

We thank Brinkmann and colleagues for their correspondence and their further investigation into these American Civil War Era vaccination strains. Here, we summarize the difficulties and caveats of work with ancient DNA.

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Duggan, A. T., Holmes, E. C., & Poinar, H. N. (2020, December 1). Response to Brinkmann et al. “Re-assembly of 19th century smallpox vaccine genomes reveals the contemporaneous use of horsepox and horsepox-related viruses in the United States.” Genome Biology. BioMed Central Ltd. https://doi.org/10.1186/s13059-020-02203-z

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