Preeclampsia Rates are Elevated during Winter Month when Sunlight Dependent Vitamin D Production is reduced

Abstract

Aim: To assess maternal vitamin D deficiency in early pregnancy and risk of preeclampsia. Settings and Design: Nested case control study. Two maternal blood samples, one at <20 wks and other at term along with cord blood at delivery were taken. Patients were classified into preeclampsia (n=57) and control group (n=178) after abstracting past medical records at delivery. Methods and material: Vitamin D was estimated by 25-Hydroxyvitamin D 125 I RIA Kit and categorized according to ACOG criteria. Statistical analysis used: Pearson chi 2, ANOVA and logistic regression were used. Linear correlation and regression coefficient was used between maternal 25(OH) D at <20 wks and term and cord serum 25(OH) D levels.