Air2Liquid Method for Selective, Sensitive Detection of Gas-Phase Organophosphates

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Abstract

Environmental hazards typically are encountered in the gaseous phase; however, selective sensing modalities for identifying and quantitating compounds of interest in an inexpensive, pseudo-real-time format are severely lacking. Here, we present a novel proof-of-concept that combines an Air2Liquid sampler in conjunction with an oil-in-water microfluidic assay for detection of organophosphates. We believe this proof-of-concept will enable development of a new platform technology for semivolatile detection that we have demonstrated to detect 50 pmoles (2 ppb) of neurotoxic organophosphates.

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Brothers, M. C., Kim, S., Adkins, D., Lewis, P., Smith, J. E., Ostojich, D., … Rubenstein, H. M. (2020). Air2Liquid Method for Selective, Sensitive Detection of Gas-Phase Organophosphates. ACS Sensors, 5(1), 13–18. https://doi.org/10.1021/acssensors.9b01624

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