Abstract
A patient with B-cell acute lymphoblastic leukemia (ALL) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had persistent, progressive pneumonia with viremia after 5 months of infection despite monoclonal antibodies, intravenous (IV) remdesivir and prolonged oral steroids. Twenty days of nirmatrelvir/ritonavir and 10 days of IV remdesivir led to full recovery.
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Ford, E. S., Simmons, W., Karmarkar, E. N., Yoke, L. H., Braimah, A. B., Orozco, J. J., … Corey, L. (2023). Successful Treatment of Prolonged, Severe Coronavirus Disease 2019 Lower Respiratory Tract Disease in a B cell Acute Lymphoblastic Leukemia Patient with an Extended Course of Remdesivir and Nirmatrelvir/Ritonavir. Clinical Infectious Diseases, 76(5), 926–929. https://doi.org/10.1093/cid/ciac868
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