Propylthiouracil-induced autoimmune disease

3Citations
Citations of this article
12Readers
Mendeley users who have this article in their library.

Abstract

Hyperthyroidism is a condition characterized by excessive production of thyroid hormones. Propylthiouracil (PTU) is commonly used as first line drug in the management of hyperthyroidism. This is a case report of 24-year-old female, a known case of hyperthyroidism since 4 years, who came with a history of fever and myalgia since 3 days and dyspnea with coughing out of blood since 1 day. Patient was taking PTU (100 mg per day) since 4 years for hyperthyroidism. Patient was immediately intubated for type-II respiratory failure. Diagnosed to be having PTU-induced autoimmune disease. PTU was stopped and treated with methylprednisolone and cyclophosphamide. Clinical features improved over a period of 8 days and discharged home successfully. Having a high suspicion for the onset of autoimmune disease in hyperthyroidism patients who are on PTU therapy and timely treatment with immunosuppressants and supportive care along with the withdrawal of the drug can make a difference in morbidity and mortality.

Cite

CITATION STYLE

APA

Paiaulla, S., Venkategowda, P. M., Rao, S. M., & Balaraju, B. (2015). Propylthiouracil-induced autoimmune disease. Indian Journal of Critical Care Medicine, 19(8), 484–486. https://doi.org/10.4103/0972-5229.162471

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free