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The neurocircuitry of fasting-induced glucocorticoid release

Cell Metabolism
DOI: 10.1016/j.cmet.2023.08.004
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Abstract

Activation of the hypothalamus-pituitary-adrenal gland (HPA) axis confers adaptations to homeostatic perturbations including food scarcity. A comprehensive new study by Douglass et al. disentangled how agouti-related peptide (AgRP)-expressing neurons of the arcuate nucleus (ARC) trigger rapid HPA-axis activation in response to fasting, which is mediated by repression of a tonic, inhibitory neuro circuit.

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APA

Jaschke, N. P., & Wang, A. (2023, September 5). The neurocircuitry of fasting-induced glucocorticoid release. Cell Metabolism. Cell Press. https://doi.org/10.1016/j.cmet.2023.08.004

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