Determination of triclosan in indonesian household, personal care, and cosmetic products by isocratic reversed-phase high-performance liquid chromatography

Abstract

Triclosan (5-chloro-2-(2,4-dichlorophenoxy) phenol) is a biocide compound commonly added to the various household, personal care, and cosmetic products. This research aims to determine triclosan content in those products by a chromatographic method. Product samples containing were analyzed using HPLC equipped with C18 column UV detection at 280 nm and mobile phase using a mixture of acetonitrile-double distilled water (75:25). All samples were confirmed to contain triclosan at levels not more than permissible level by the regulation in Indonesia.