Interstrand interactions between side chains in a double-helical foldamer

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Abstract

(Figure Presented) Hairy molecules! The numerous benzyloxy side chains sticking out of a helically folded pyridine carboxamide oligomer bring about considerable stabilization to its double-helical conformation. The structure of the duplex was studied both in solution and in the solid state. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

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Haldar, D., Jiang, H., Léger, J. M., & Huc, I. (2006). Interstrand interactions between side chains in a double-helical foldamer. Angewandte Chemie - International Edition, 45(33), 5483–5486. https://doi.org/10.1002/anie.200600698

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