DNAPROBE, a computer program which generates oligonucleotide probes from protein alignments

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Abstract

We describe a program to assist in designing oligonucleotide probes on the basis of protein alignments and the codon usage of the target organism. If necessary, the input sequences can be weighted to neutralise the effect of closely similar sequences or to bias the output in favour of a particular taxon.

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Drummond, M., & Stamper, J. (1999). DNAPROBE, a computer program which generates oligonucleotide probes from protein alignments. Nucleic Acids Research, 27(17), 3493. https://doi.org/10.1093/nar/27.17.3493

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