Abstract
Late adenovirus messenger RNA was annealed to complementary regions of partially melted viral doublestranded DNA. The RNA x DNA hybrid regions within the DNA molecules were visualized as loops in the electron microscope. Loops occurred at several regions of the DNA, most frequently, however, at a location near the center of the molecule. This hybridization technique appears well suited for an accurate mapping of messenger RNA, as well as for studies of RNA processing.
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CITATION STYLE
Westphal, H., Meyer, J., & Maizel, J. V. (1976). Mapping of adenovirus messenger RNA by electron microscopy. Proceedings of the National Academy of Sciences of the United States of America, 73(6), 2069–2071. https://doi.org/10.1073/pnas.73.6.2069
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