Enhancement of antibody titers against Newcastle Disease Virus in vaccinated chicks by administration of Phyto V7

Abstract

Phyto V7is a complexof phytochemicals that has been found to stimulate the immune responses in AIDS patients and in Human Papilloma Virus infected individuals. Here we report the capacity of Phyto V7 to stimulate humoral immune response in chicks vaccinated against Newcastle Disease Virus. The mean antibody titers against Newcastle Disease Virus were >50% higher in chicks fed with Phyto V7 as compared to chicks fed with regular broiler feed (p<0.01). While the exact mechanism by which Phyto V7 affects the immune system needs to be elucidated, this study clearly supports the notion that Phyto V7 has immune-stimulatory properties. Further studies are needed to clearly establish if Phyto V7 administration can increase successful vaccination rates against Newcastle Disease Virus and other viruses in chicks and other animals.The capacity of Phyto V7 to enhance immune responses in humans to vaccines should be studied too. © 2013 Perelman D, et al.