High‐flux hemodialysis after administering high‐dose methotrexate in a patient with posttransplant lymphoproliferative disease and impaired renal function

Abstract

A young patient develops cerebral posttransplant lymphoproliferative disorder. Despite concurrent significantly impaired transplant kidney function use of add‐on high‐flux hemodialysis for additional clearance made the administration of high‐dose methotrexate feasible in this patient without occurence of acute chronic kidney failure and significant hematological toxicity.