Nitrate-Induced Oxidative Stress and the Effects of Dietary Antioxidant Vitamins C, E And A: Insights from Experimental and Clinical Studies

Abstract

Various studies on nitrates and nitrites including their widespread applications, mechanisms of action and biological effects due to their ability to induce oxidative stress have been reviewed. The current vigorous research efforts to explore the potential uses of antioxidants in various disease conditions have been critically examined and presented. The review is also focused on Vitamins C, E and A, among other antioxidants, as they can be chiefly obtained in natural form from fruits and vegetables in almost all parts of the world.