DENGUE PREVENTION AND TREATMENT: A SCOPING REVIEW

Abstract

Dengue is an arbovirus with significant socioeconomic impact worldwide and in Brazil. This scenario led the Brazilian Ministry of Health to launch a preventive manual in 2009 and a treatment manual in 2016 to deal with this disease. Between the year of these publications and today, numerous therapeutic options emerged and were discussed in the literature. So, this independent research aims to investigate dengue treatment methods presented in the literature. A scoping review was forged following the Problem, Concept, and Context (PCC) strategy, following the guiding questions: “What methods for preventing dengue have been presented in the scientific literature in the last 14 years?” “What methods for treating dengue have been presented in scientific literature in the last 8 years? The literature search was performed in PubMed, LILACS, Cochrane, and Scielo using the descriptors “Dengue AND Prevention” and “Dengue AND treatment”. Almost 18 thousand studies were evaluated. Of these, 7,474 discussed dengue preventive measures, while only 17 were included in the final text. Simultaneously, 10,462 were dedicated to dengue treatment, with just 28 articles included in the final text. Numerous preventive and therapeutic measures have emerged in recent years; however, further comprehensive studies are imperative to substantiate their effectiveness on a large scale and assess their viability for widespread implementation. In this sense, vaccines and supportive measures, such as fluid therapy, remain primary interventions in dengue prevention and treatment, serving as cornerstones in mitigating the impact of this disease.