When size matters: A novel compact Cas12a variant for in vivo genome editing

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Abstract

A new study characterizes and improves a novel small Cas12a variant before adapting it for in vivo genome editing by delivery via adeno-associated virus (AAV) vectors, showcasing the potential of small CRISPR systems and their compatibility with viral vectors.

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APA

Bubeck, F., & Grimm, D. (2024). When size matters: A novel compact Cas12a variant for in vivo genome editing. PLoS Biology, 22(7 July). https://doi.org/10.1371/journal.pbio.3002637

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