Diabetes and the blood - White cells and platelets

Abstract

Haematological abnormalities affecting most cell types are common among people with diabetes. WBCC changes may highlight inflammation or immunological problems before or during the onset of diabetes. Neutrophil malfunction contributes to the greater infection risk among those with diabetes, and to the difficulty in treating infections. Platelet abnormalities contribute to cardiovascular disease in diabetes, particularly via atherothrombosis. While aspirin is not recommended for primary prevention in people with diabetes, those with proven cardiovascular disease or thromboembolism should receive usual antiplatelet therapy. Improving blood glucose control may improve WBC and platelet function.