Abstract
A small focused library which comprised of l-AA lactone derivatives was built with a facile method. This reported method was optimized by modifying the acidity of the solvent. As a result, 12 l-AA lactones were synthesized. Among these lactones, lactones 8–12 were new compounds. The cytotoxicity of these synthetic compounds were investigated.
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Shao, L. D., Wu, Y. N., Xu, J., He, J., Zhao, Y., Peng, L. Y., … Zhao, Q. S. (2014). Synthesis of l-Ascorbic Acid Lactone Derivatives. Natural Products and Bioprospecting, 4(3), 181–188. https://doi.org/10.1007/s13659-014-0022-6
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