mirtazapine-related manic / hypomanic shift: Mini review and case report

Abstract

Mirtazapine-related manic / hypomanic shift: mini review and case report Mirtazapine is a pharmacological agent frequently used both as an antidepressant and as a hypnotic sedative agent. However, manic shift, an important side effect of other antidepressants, has not been adequately addressed in the treatment of mirtazapine, and the evidence has been only available from case reports. This mini-review and case report aimed to compile case reports on mirtazapine related manic shifts and to report a case where a manic shift was determined relatively early compared to that in these cases.