Abstract
Rapid access to rigid rods: A method is described for the synthesis of 3-O-alkylated aromatic oligobenzamide foldamers that could be used for assembly of libraries of α-helix mimetic inhibitors of protein-protein interactions (see scheme; Fmoc=9-fluorenylmethoxycarbonyl). © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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Murphy, N. S., Prabhakaran, P., Azzarito, V., Plante, J. P., Hardie, M. J., Kilner, C. A., … Wilson, A. J. (2013). Solid-phase methodology for synthesis of O-alkylated aromatic oligoamide inhibitors of α-helix-mediated protein-protein interactions. Chemistry - A European Journal, 19(18), 5546–5550. https://doi.org/10.1002/chem.201204098
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