The X-inactivation yo-yo

  • Reik W
  • Ferguson-Smith A
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Abstract

In female mammals, one of two X chromosomes has to be shut down during early development. To what extent does this ‘imprinted X-chromosome inactivation’ involve the history of the chromosome?

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Reik, W., & Ferguson-Smith, A. C. (2005). The X-inactivation yo-yo. Nature, 438(7066), 297–298. https://doi.org/10.1038/438297a

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