Histologic patterns of neuroblastoma related to prognosis and clinical staging

Abstract

Eighty‐three tumors have been examined histologically. They have been graded according to evidence of maturation; the grades have been related to prognosis and clinical staging, and the results submitted to statistical analysis. Fourteen of these patients are still alive at least 3 years after diagnosis; their tumors show a high level of histologic differentiation. The histologic grades are also related to the age of the patient and the site of the tumor. We have also assessed the degree of lymphocytic infiltration within the tumors, but no significant relationship between this and prognosis could be established. Copyright © 1974 American Cancer Society