Has droperidol an atropinic effect?

Abstract

The action of droperidol on the tachycardia produced by atropine and on the serum concentration of cholinesterases was observed during balanced anaesthesia. Without atropine, the mean heart rates of patients who received fentanyl or fentanyl plus droperidol were similar. Atropine increased heart rate only in the presence of droperidol (P<0.001) (fentanyl v. fentanyl plus droperidol: (P<0.05). Droperidol inhibited serum cholinesterases (P<0.05); this effect was independent of atropine. © 1979 Macmillan Journals Ltd.