Abstract
Patients with multidrug-resistant tuberculosis who received regimens containing high-dose isoniazid (INHHD) had similar time to culture conversion and treatment outcomes as patients who received regimens with bedaquiline. INHHD is an inexpensive and safe medication that may contribute additive efficacy in combination regimens.
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Walsh, K. F., Vilbrun, S. C., Souroutzidis, A., Ellis, J., Delva, S., Joissaint, G., … Koenig, S. P. (2022). Time to Culture Conversion of Bedaquiline and High-Dose Isoniazid for Drug-Resistant Tuberculosis. Open Forum Infectious Diseases, 9(9). https://doi.org/10.1093/ofid/ofac440
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