Abstract
Four new 7, 20-epoxy-ent-kauranoids, rubluanins A-D (1-4) and eleven known ones, were isolated from Isodon rubescens var. lushanensis, and their structures were elucidated by spectroscopic analysis. Compounds 2-14 were evaluated for their cytotoxicity in several human tumor cell lines (U937, Jurkat, HL-60, K562, SGC790, and HepG2). Among the compounds, lasiokaurin (13) showed significant cytotoxic activity of 0.62 μM (IC50) in U937 cells. © 2010 Pharmaceutical Society of Japan.
Author supplied keywords
Cite
CITATION STYLE
Zhang, H. B., Pu, J. X., Wang, Y. Y., He, F., Zhao, Y., Li, X. N., … Sun, H. D. (2010). Four new ent-kauranoids from Isodon rubescens var. lushanensis and data reassignment of dayecrystal B. Chemical and Pharmaceutical Bulletin, 58(1), 56–60. https://doi.org/10.1248/cpb.58.56
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
