Two new diphenylethylenes from arundina graminifolia and their cytotoxicity

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Abstract

Two new diphenylethylenes, gramniphenols H and I (1 and 2), together with six known diphenylethylenes (3- 8), were isolated from Arundina graminifolia. The structures of 1-8 were elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. Compounds 1 and 2 were evaluated for their cytotoxicity against five human tumor cell lines. Compound 1 showed cytotoxicity against PC3 cells with IC50 value of 3.5 μM. Compound 2 showed cytotoxicity against NB4 and PC3 cells with IC50 values of 3.6 and 3.8 μM,respectively.

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Li, Y. K., Zhou, B., Ye, Y. Q., Du, G., Niu, D. Y., Meng, C. Y., … Hu, Q. F. (2013). Two new diphenylethylenes from arundina graminifolia and their cytotoxicity. Bulletin of the Korean Chemical Society, 34(11), 3257–3260. https://doi.org/10.5012/bkcs.2013.34.11.3257

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