Post Covid19 Vaccination Acute Disseminated Encephalomyelitis: A Case Report in Bangladesh

Abstract

Acute disseminated encephalomyelitis (ADEM) is an inflammatory usually monophasic demyelinating disease of the central nervous system. ADEM is one of several categories of primary inflammatory demyelinating disorders of the central nervous system. Other diseases include multiple sclerosis, optic neuropathy, acute transverse myelitis, and neuromyelitis optica (Devic’s disease). Post infectious And post-vaccination encephalomyelitis make up most of cases. Post-vaccination ADEM has been associated with several vaccines such as rabies, diphtheria–tetanus–polio, smallpox, measles, mumps, rubella, Japanese B encephalitis, pertussis, influenza and hepatitis B vaccine. We found a case of ADEM which is associated Covid19 vaccination as the precipitating factor. A patient presenting with altered level of consciousness & seizure within 3 weeks of ‘‘messenger RNA Covid 19 vaccination and diagnosed as ADEM after all investigations & completely cured after conservative management.