Bioinformatics Approach for COVID-19 (Coronavirus) Disease Prevention Treatment and Drug Validation

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Abstract

Objectives: To determine the impact of Hydroxychloroquine on COVID special protease. Methods: PyMOL software is used to find all possible residual rotameters and probabilities. AutoDock software is used to calculate and predict the interaction of molecules. Results: Hydrochloroquine binds and is released through Protease 6y84 and 7buy and controls their actions in the body. Conclusion: Drug designing and docking is helpful for the particular diseases. It helps us predict the intermolecular framework formed between a protein or a small molecule.

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Mishra, S., Jain, P. A., Ahmad, S., & Mishra, S. (2020). Bioinformatics Approach for COVID-19 (Coronavirus) Disease Prevention Treatment and Drug Validation. Eurasian Journal of Medicine and Oncology, 4(3), 234–238. https://doi.org/10.14744/ejmo.2020.97358

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