Pharmacokinetics of orally administered melatonin in critically ill patients

  • Moroni B
  • Mistraletti G
  • Reiter R
  • et al.
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Abstract

Critically ill patients exhibit reduced melatonin secretion, both in nocturnal peaks and basal daytime levels. Oral melatonin supplementation may be useful for known sedative and antioxidant properties.

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Moroni, B., Mistraletti, G., Reiter, R., Esposti, R., D’Angelo, E., Formenti, P., … Iapichino, G. (2010). Pharmacokinetics of orally administered melatonin in critically ill patients. Critical Care, 14(Suppl 1), P494. https://doi.org/10.1186/cc8726

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