Abstract
Synthesis of a novel series of structurally related pyrazoloquinoline nucleosides is described. All the newly synthesized compounds were examined for their in vitro antiviral activity against herpes simplex type-1 as shown by two different bioassays, namely; crystal violet staining or the MTS tetrazolium dye measurement. The acute toxicity (LD50) values of the biologically active compounds were determined.
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CITATION STYLE
Bekhit, A. A., El-Sayed, O. A., Aboul-Enein, H. Y., Siddiqui, Y. M., & Al-Ahdal, M. N. (2004). Synthesis of aldehydo-sugar derivatives of pyrazoloquinoline as inhibitors of herpes simplex virus type 1 replication. Journal of Enzyme Inhibition and Medicinal Chemistry, 19(1), 33–38. https://doi.org/10.1080/14756360310001650219
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