First total synthesis of justicidone, a p-quinone-lignan derivative from Justicia hyssopifolia

Abstract

The first synthesis of justicidone (4-(1′,3′-Benzodioxol- 5′-yl)-6-methoxynaphtho[2,3-c]furan-1,5,8(3H)-trione) was carried out from piperonal, as a starting compound, through a lineal process using well known reactions. © 2005 Pharmaceutical Society of Japan.