From the urea cycle to autophagy: Alfred J. Meijer

Abstract

Now that many of the components of the autophagy machinery have been identified, in particular the autophagy-related (Atg) proteins, increasing focus is being directed toward the role of autophagy in health and disease. Accordingly, it is of ever-greater importance to understand the central role of autophagy in cellular metabolism, a point with which many people will likely agree. However, in our rush to understand autophagy's function in metabolism, we tend to over-look the role of metabolism in regulating autophagy, even though substantial work has been done on this topic. One of the pioneers in this area is Alfred "Fred" J. Meijer. © 2011 Landes Bioscience.