Deubiquitinases in cancer

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Abstract

Deubiquitinases are deubiquitinating enzymes (DUBs), which remove ubiquitin from proteins, thus regulating their proteasomal degradation, localization and activity. Here, we discuss DUBs as anti-cancer drug targets.

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Wei, R., Liu, X., Yu, W., Yang, T., Cai, W., Liu, J., … Liu, S. (2015). Deubiquitinases in cancer. Oncotarget, 6(15), 12872–12889. https://doi.org/10.18632/oncotarget.3671

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